Green tea compounds block key enzyme that allows coronavirus to replicate – study

by EzekielDiet.com
Posted on Dec 16, 2020

Tuesday, December 15, 2020 by:

(Natural News) A study published in the journal Frontiers in Plant Science shows that chemical compounds in green tea and other plant-based foods can block the activity of a key enzyme in the replication of SARS-CoV-2, the virus responsible for COVID-19.

Researchers at North Carolina State University (NC State) found that many polyphenols in these foods are able to inhibit the function of “main protease” (Mpro) by directly binding to it. Without the activity of this enzyme, SARS-CoV-2 cannot remain viable for long.

“Mpro in SARS-CoV-2 is required for the virus to replicate and assemble itself. If we can inhibit or deactivate this protease, the virus will die,” said co-author De-Yu Xie, a professor of plant and microbial biology at NC State. The study was published on Nov. 30 and was funded by the U.S. Department of Agriculture.

Flavanols inhibit the activity of a key coronavirus replication enzyme

For their experiment, Xie and co-author Yue Zhu used the Mpro of SARS-Cov-2 to screen polyphenols derived from various food sources and identify candidate inhibitors. The team chose 12 plant compounds that belong to a group of polyphenols called flavonoids. These plant compounds are responsible for the vivid colors of many fruits and vegetables and are known for their potent antiviral, antioxidant and anti-inflammatory properties.

“One of our lab’s focuses is to find nutraceuticals in food or medicinal plants that inhibit either how a virus attaches to human cells or the propagation of a virus in human cells,” explained Xie.

He and Zhu reported that computer simulations predicted that all 12 compounds they chose can bind to different sites on Mpro. These simulations also showed that Mpro has a pocket-like portion that can be “filled” by the plant compounds. Once filled, the protease loses many of its important functions.

The researchers identified the compounds present in green tea, two varieties of muscadine grapes, cacao and dark chocolate as the flavanols with the highest inhibitory activity. Those found in green tea and muscadine grapes, however, were more effective at inhibiting Mpro activity than compounds in cacao and dark chocolate. (Related: Green tea, zinc proving to be BETTER than hydroxychloroquine at fighting coronavirus infections.)

“Green tea has five tested chemical compounds that bind to different sites in the pocket on Mpro, essentially overwhelming it to inhibit its function,” said Xie. “Muscadine grapes contain these inhibitory chemicals in their skins and seeds. Plants use these compounds to protect themselves, so it is not surprising that plant leaves and skins contain these beneficial compounds.”

Plant-based drinks like green tea can kill coronavirus

An earlier study also reported that plant-based beverages like green tea can kill SARS-CoV-2 when incubated with the virus in vitro. German researchers discovered this after examining the ability of green tea, black chokeberry juice, pomegranate juice and elderberry juice to inactivate different viruses, including SARS-CoV-2.

The researchers mixed the beverages with the viruses and incubated them at room temperature. After five minutes, the researchers found that black chokeberry juice reduced the infectivity of viruses by a considerable margin compared to the control. Green tea, elderberry juice and pomegranate juice also decreased viral infectivity substantially.

Black chokeberry juice inactivated about 97 percent of SARS-CoV-2 after five minutes, while green tea and pomegranate juice inactivated about 80 percent of the virus. Meanwhile, elderberry juice had no effect on SARS-CoV-2. The researchers said that the beverages had rapid and robust antiviral activities that may have stemmed from their acidity, which can directly inactivate viruses, and the presence of polyphenols like flavonoids, catechins and tannins.

Because of their findings, the researchers believe oral rinsing with these beverages can help reduce viral loads, especially since transmission occurs via the nose and throat for respiratory viruses like SARS-CoV-2. Beverages like green tea and black chokeberry juice are also safer to use than antiseptic oral rinses, which contain harsh chemical ingredients.

For more stories about foods that can help fight the coronavirus, visit CoronavirusFoods.com.

Sources include:

Futurity.org

FrontiersIn.org

News-Medical.net

Source:  https://www.naturalnews.com/2020-12-15-green-tea-compounds-block-enzyme-coronavirus-replication.html

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girişimajbet girişHoliganbet girişJojobet girişAnadolucasino girişArtemisbet girişbelugabahis girişbetvole girişinterbahis girişmilanobet girişZeytinburnu EscortYeşilköy EscortYenibosna EscortÜmraniye EscortTopkapı EscortTaksim EscortSuadiye EscortSınırsız EscortŞişman EscortŞişli EscortŞirinevler EscortSilivri EscortPendik EscortOrtaköy EscortOlgun EscortNişantaşı EscortMerter EscortMecidiyeköy EscortMaslak EscortMaltepe EscortMahmutbey EscortLevent EscortKurtköy EscortKüçükyalı EscortKüçükçekmece EscortKartal EscortKağıthane EscortKadıköy Escortİstanbul Escortİkitelli EscortHaramidere EscortHalkalı EscortGöztepe EscortGenç EscortFlorya EscortFındıkzade EscortFatih EscortEtiler EscortEsenyurt EscortEscort NumaralarıEscort BayanlarErenköy EscortElit Escortçekmeköy escortÇıtır Escortşerifali escortCihangir Escortümraniye escortüsküdar escortCevizli EscortCennet Mahallesi Escortsuadiye escortÇapa Escortkadıköy escortÇağlayan Escortgöztepe escortBüyükçekmece Escortbostancı escortgöztepe escortBostancı EscortBeyoğlu Escortsuadiye escorterenköy escortbostancı escortanadolu yakası escortavrupa yakası escortBeylikdüzü EscortBeşiktaş Escortanadolu yakası escortBayrampaşa EscortBaşakşehir Escortümraniye escortBakırköy Escortkadıköy escortBahçelievler Escortbostancı escortBağdat Caddesi Escortataşehir escortBağcılar Escortcevizli escortatalar escortmaltepe escortAvrupa Yakası Escortkartal escortmaltepe escortAvcılar EscortAtaşehir Escortümraniye escortsupertotobetrestbet girisbetpas girisbetbabayurtdisiaugenoperationbotox bruisinghepsibahisrexbetsuperbetinbetsatbets10romabettarafbetbetparkhilbetonbahisbahsegelbahigowinxbetelitbahisdinamobetbetmatiktimebetgebze escortleopard honeyAnkara escortUlus escortTunalı escortTandoğan escortSıhhiye escortRus escortMamak escortMamak escortGölbaşı escortCinsel sağlık ürünleriCinsel performans ilaçlarıCialis fiyatCialis 20 mg fiyatCialis 100 mg fiyatCialis 30 lu tablet fiyatViagra fiyatViagra 100 mg fiyatViagra 30 lu fiyatViagra 4 lü tablet fiyatıVega 100 mgVega 100 mg fiyatVega 100 mg eczaneKamagra jelKamagra Jel fiyatKamagra jel eczaneSertleştirici haplarGeciktirici ürünlercialiscinsel sağlık ürünleribayan azdırıcı fiyatkadın azdırıcı damlasertleştirici ilaçlarcialis fiyatviagra fiyatpenis büyütücükamagra jelgeciktirici spreycialis 20 mgcialis 100 mgviagra 30 luen iyi penis sertleştirici ilaçsertleştirici haplarelazığ escort bayanhasta yataklarıkent switch fiyatmarlboro shuffleparliament aqua bluemarlboro double fusionmarlboro shufflekent switchdjarum blackdjarum blackAnadolu yakası escortAtaşehir escortBostancı escortErenköy Escortavrupa yakası escortAtaköy EscortAvcılar EscortBahçeşehir Escortözel escortlaranal escortçıtır escortelit escortAnadolu Yakası escortAtaşehir escortbağdat caddesi escortBostancı escortGöztepe Escortİstanbul EscortKadıköy EscortKartal EscortKurtköy EscortMaltepe EscortPendik EscortŞerifali EscortTuzla EscortÜmraniye escortÜsküdar EscortAnadolu Yakası EscortAtaşehir escortBostancı EscortGöztepe EscortAvrupa Yakası EscortAksaray escortAtaköy EscortAvcılar Escortİstanbul EscortAtaşehir Elit EscortAtaşehir Esmer EscortAtaşehir Genç EscortAtaşehir Olgun EscortAtaşehir Sarışın EscortAtaşehir Şişman EscortAtaşehir Sınırsız EscortAtaşehir Ucuz EscortAtaşehir Yabancı EscortAteşehir Escort BayanBağdat Caddesi EscortBağdat Caddesi Olgun EscortBağdat Caddesi Sarışın EscortBağdat Caddesi Şişman EscortBağdat Caddesi Ucuz EscortBağdat Caddesi Yabancı EscortBostancı Elit EscortBostancı Çıtır EscortBostancı EscortBostancı Esmer EscortBostancı Olgun EscortBostancı Sarışın EscortBostancı Yabancı EscortGöztepe EscortGöztepe Genç EscortGöztepe Olgun EscortGöztepe Şişman EscortGöztepe Sınırsız EscortGöztepe Ucuz EscortKadıköy Anal EscortKadıköy Elit EscortKadıköy EscortKadıköy Eskort BayanlarKadıköy Genç EscortKadıköy Yabancı EscortKartal Çıtır EscortKartal EscortKartal Eskort BayanlarKartal Esmer EscortKartal Sarışın EscortKartal Sınırsız EscortKartal Ucuz EscortKaynarca EscortKaynarca Genç EscortKaynarca Olgun EscortKaynarca Şişman EscortKurtköy EscortKurtköy Escort BayanKurtköy Ucuz EscortKurtköy Yabancı Escort BayanMaltepe Anal EscortMaltepe EscortMaltepe Genç EscortMaltepe Olgun EscortMaltepe Şişman EscortPendik EskortPendik Eskort BayanlarPendik Sarışın EscortPendik Şişman EscortPendik Sınırsız EscortPendik Ucuz EscortTuzla Anal EscortTuzla Elit EscortTuzla EscortTuzla Yabancı EscortÜmraniye EscortÜmraniye Masöz EscortÜmraniye Olgun EscortÜmraniye Ucuz Escortepoksi zeminepoksi zemin kaplamaepoksi yol çizgisişişli escortAcıbadem Escortİçerenköy EscortKozyatağı EscortKüçükyalı EscortKadıköy EscortKartal EscortMaltepe EscortPendik EscortKurtköy EscortŞerifali EscortAnadolu Yakası EscortKadıköy EscortAtaşehir EscortBostancı EscortAtaşehir EscortKadıköy EscortKurtköy EscortAnadolu Yakası EscortAnadolu Yakası EscortAtaşehir EscortBostancı EscortKadıköy EscortAnadolu Yakası EscortKadıköy EscortAtaşehir EscortBostancı EscortMaltepe EscortGöztepe EscortPendik EscortErenköy EscortGöztepe EscortSuadiye EscortGöztepe EscortMaltepe EscortŞerifali EscortKartal EscortKurtköy EscortPendik EscortKurtköy EscortPendik EscortAnadolu Yakası EscortKartal EscortMaltepe EscortAnadolu Yakası EscortKartal Escort BayanKurtköy Escort BayanMaltepe Escort BayanPendik Escort BayanAnadolu Yakası EscortKartal EscortKurtköy EscortMaltepe EscortPendik EscortTuzla EscortKurtköy EscortPendik EscortTuzla EscortAnadolu Yakası EscortMaltepe EscortKartal EscortBostancı EscortÜmraniye EscortAnadolu Yakası EscortKadıköy EscortAtaşehir EscortTuzla EscortGebze EscortAydınlı EscortMutlukent EscortPendik EscortAnadolu Yakası EscortKurtköy EscortÜmraniye EscortBostancı EscortKartal Escort BayanPendik Escort BayanKurtköy Escort BayanMaltepe EscortAnadolu Yakası EscortBostancı EscortKartal EscortMaltepe EscortÜmraniye Escortbağdat caddesi escortgöztepe escortistanbul escortkartal escortkurtköy escortmaltepe escortpendik escorttuzla escortüsküdar escortataköy escortavcılar escort bayanavrupa yakası escortbahçeşehir escortbakırköy escortbeşiktaş escortbeylikdüzü escorterenköy escortetiler escortgöztepe escortikitelli escortkartal escortkurtköy escortmaltepe escortmecidiyeköy escortpendik escortşirinevler escortşişli escortsoğanlık escortataşehir escortkaynarca escortümraniye escortgebze escorttuzla escortavrupa yakası escortavrupa yakası escortavrupa yakası escortavrupa yakası escortavrupa yakası escortavrupa yakası escortavrupa yakası escortavrupa yakası escortavrupa yakası escortatalar escortcevizli escortescort bayanmaltepe escortbeylikdüzü escortavcılar escortesenyurt escortbahçeşehir escortşirinevler escortataköy escortbeylikduzuescortev.comescort beylikdüzüWhatsapp aerobeylikdüzü eskortbahariye escortmoda escortsex hikayeleriadana escortadıyaman escortafyon escortağrı escortaksaray escortamasya escortankara escortantalya escortantep escortardahan escortartvin escortaydın escortbalıkesir escortbartın escortbatman escortbayburt escortbilecik escortbingol escortbitlis escortbolu escortburdur escortbursa escortçanakkale escortçankırı escortçorum escortdenizli escortdiyarbakır escortdüzce escortedirne escortelazığ escorterzincan escorterzurum escorteskişehir escortgiresun escortgümüşhane escorthakkari escorthatay escortığdır escortısparta escortistanbul escortizmir escortizmit escortkarabük escortkaraman escortkars escortkastamonu escortkayseri escortkıbrıs escortkilis escortkırıkkale escortkırklareli escortkırşehir escortkocaeli escortkonya escortkütahya escortmalatya escortmanisa escortmaraş escortmardin escortmersin escortmuğla escortmuş escortnevşehir escortniğde escortordu escortosmaniye escortrize escortsakarya escortsamsun escortsiirt escortsinop escortşırnak escortsivas escorttekirdağ escorttokat escorttrabzon escorttunceli escortzonguldak escorturfa escortuşak escortvan escortyalova escortyozgat escorterkeklerde sertleşmeye iyi gelen ilaçlarsertleştirici hap eczane fiyatlarıyakacik escortsisli escortvega 100 mg hapseofuck googledolandırıcı hesap satışıviagrabacklink almetin2 pvppvp metin2metin2emek serveradana escortadana escortanadolu yakasi escortpendik escortistanbul escort